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Stem cell donations

Haematopoietic stem cells are bone marrow cells that give rise to the various types of blood cells. They are administered to patients suffering from an incurable bone marrow pathology.

What are haematopoietic stem cells?

Haematopoietic stem cells (HSCs) are the cells that are mainly located inside the bone marrow and who go on to produce the bulk of the blood cells (red blood cells, white blood cells and platelets). As these blood cells mature, they are released into the blood stream where they perform their work. These cells enable the blood to be constantly replenished.

Why become a haematopoietic stem cell donor?

Haematopoietic stem cell donations (HSCs) allow people suffering from a haematopoietic disorder (disorders that prevent the production of these cells) to survive. These cells are used to treat the people suffering from leukaemia, cancer or anaemia.
Your generous gesture will enable us to:

•    To increase the likelihood of finding a compatible donor in the National Register of Stem Cell Donors (officially known as the Marrow Donor Program Belgium Registry). 
•    To save a patient thanks to the transplantation of your HSCs if the cells are compatible with his.

Who can sign up as a voluntary HSC donor?

Anyone aged 18 to 40 who complies with the eligibility criteria to donate blood. When your has been established, this will be recorded in the National Register of Stem Cell Donors, which will increase the likelihood of finding a compatible donor for a patient awaiting haematopoietic (bone marrow stem cell) transplantation.
It is worth noting that haematologists prefer to transplant HSCs from young men, as women are often seen to develop antibodies after giving birth, which may reduce the chances of success of the graft.

Signing up with the National Register in 3 steps

Signing up as a stem cell donor is a long-term commitment as you may be asked to come forward to make an HSC donation at any time in the near or distant future, never around the time you register. It could be anything from several weeks to several years even, between the time when you register and the time you are called up to come in to donate HSC cells for a compatible patient.

It is important that you read this page and make enquiries with our collection teams if you have any questions and also give your commitment a good deal of thought.
For further information, please consult our brochure on stem cell donations.

1. Pre-registration

You can pre-register at the National Register’s website at www.mdpb.be. You will be sent a confirmation mail, inviting you to call round to a blood collection centre or to attend a blood collection.



You will first have a confidential medical interview ;
You will then be asked to complete and sign the “Informed consent form with a view to an HSC donation”;
We will then collect a blood sample from you for testing in order to establish your “HLA type”. This typing test enables us to determine the antigens carried by your white blood cells and your profile may be compared with that of patients who are awaiting transplantation.


If nothing stands in the way, your registration in the Register will be confirmed and you will be sent a donor card by post. Your details will be kept on file until you reach the age 60, unless you were to cancel your availability as a donor.


Signing up with the National Register of Stem Cell Donors is a personal decision that needs to be duly considered as it involves a real commitment: you accept, if you are compatible with a patient, to make yourself available for collection. You undertake to inform the Blood Service of the Belgian Red Cross of all and any changes in your health status or your administrative details. You accept to donate your stem cells to anyone who may need them. You are free to withdraw at any time without having to state reasons.

How does haematopoietic stem cell donation work?


If you are found to be compatible with a patient someday, we will contact you to make an appointment with the doctor in charge of the collection. You will have a medical examination as well as additional examinations. If you comply with all the requisites, we can go ahead with the actual collection. 


In order to collect the HSCs, you will be given a subcutaneous injection with a growth factor (G-CSF) once a day over 4 to 5 days, which will increase the production of HSCs in your blood. The collection is similar to donating platelets: your blood goes into a machine which selects the HSCs. The other cells are immediately returned to your body. All materials used are sterile and single use. You will neither be anaesthetised nor admitted into hospital. The collection procedure takes 2 to 4 hours. If necessary, a second collection may be performed the next day. Please be aware that you may donate your HSCs just once to a donor who is not related to you. However, if among your siblings you are compatible with a member of your family, you may donate against without any problem. As soon as you have made your donation, your name will be taken off the list of the National Belgian Register of Stem Cell Donors.


We will perform medical check-up at one week, one month, one year and five years after your donation to make sure your body has properly recovered. 


Do you have questions regarding stem cell donations?

Consult our FAQ

Are you considering to sign up with the Register of Stem Cell Donors? 

Do you have questions?


Contact us at 0800 92 245 or send us a mail at info@croix-rouge.be.